Gene interactions and pathways from curated databases and text-mining

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AP2S1 — EGF

Pathways - manually collected, often from reviews:

Text-mined interactions from Literome

Sakaguchi et al., Biochem Biophys Res Commun 2001 : These results suggest that EGF stimulates Shc-AP2 complex formation and association of Shc-AP2 complexes with EGF receptors
Yun et al., J Biol Chem 2008 : The interaction of PLC-epsilon with AP2 was responsible for the suppression of EGF receptor down-regulation, since a perturbation in this interaction abolished this effect