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HDAC7 — PDGFB

Text-mined interactions from Literome

Ullerås et al., Exp Cell Res 2001 (Adenocarcinoma...) : Inhibition of histone deacetylase activity causes cell type-specific induction of the PDGF-B promoter only in the absence of activation by its enhancer
Zhang et al., J Biol Chem 2010 : Importantly, our data also revealed that PDGF-BB regulated HDAC7 expression not through phosphorylation of HDAC7 but through transcriptional activation ... Mutation of the Sp1 site within this PDGF-BB-responsive element abolished PDGF-BB induced HDAC7 activity ... Moreover, we also demonstrated that knockdown of Sp1 abrogated PDGF-BB induced HDAC7 up-regulation and SMC differentiation gene expression in differentiating ES cells, although enforced expression of Sp1 alone was sufficient to increase the activity of the Hdac7 promoter and expression levels of SMC differentiation genes