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EPHA4 — RAC1

Pathways - manually collected, often from reviews:

• Reactome Reaction: EPHA4 → RAC1 (reaction) Marston et al., Nat Cell Biol 2003, Yoo et al., Mol Cells 2010
• Reactome Reaction: EPHA4 → RAC1 (indirect_complex) Marston et al., Nat Cell Biol 2003

Text-mined interactions from Literome

Hunter et al., Mol Cell Biol 2006 : The EphA receptor mediated angiogenic response is dependent on activation of Rho family GTPase Rac1 and is regulated by phosphatidylinositol 3-kinase
Bisson et al., Mol Biol Cell 2007 : Despite this, neither Cdc42 nor Rac activities are down-regulated by EphA4 activation or by the xPAK1-GBD
Takeuchi et al., FEBS Lett 2009 : EphA4 bound to beta2-chimaerin through its kinase domain and promoted binding of Rac1 to beta2-chimaerin