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CXCL12 — IL1A
Text-mined interactions from Literome
Han et al., J Clin Invest 2001
:
TNF-alpha treatment mimicked
SDF-1 alpha
induction of NF-kappa B,
IL-1 alpha/beta , and RANTES, as well as cell death ; neutralizing antibodies against TNF-alpha opposed these responses
Daly et al., Oral Oncol 2008
(Carcinoma, Squamous Cell...) :
IL-1alpha and OSCC cell conditioned medium both
stimulated HGF and
SDF-1 expression, while TGF-beta(1) inhibited production of each factor
Sanmiguel et al., Cell Signal 2009
(Psoriasis) :
Expression of CXCL9,
CXCL10 and CXCL11 mRNAs was also increased in
response to
IL-1 , but protein could only be detected in medium from cells treated with IFN-gamma alone or in combination with IL-1
Ohashi et al., Hepatology research : the official journal of the Japan Society of Hepatology 2009
:
Results : ( i )
IL-1alpha up-regulated mRNA levels of
CXCL8 , CXCL10, and CCL2
Kogan-Sakin et al., Carcinogenesis 2009
:
Prostate stromal cells produce CXCL-1,
CXCL-2 , CXCL-3 and IL-8 in
response to epithelia secreted
IL-1
Voronov et al., J Immunotoxicol 2010
(Fibrosarcoma...) :
SDF-1 and IL-6, each
induced by
IL-1 , were the two major cytokines whose levels differed in cell lines with or without IL-1
Olaru et al., J Invest Dermatol 2010
(Staphylococcal Skin Infections) :
IL-1alpha and IL-1beta
increased mRNA production and protein secretion of the neutrophil chemotactic CXCL1,
CXCL2 , and IL-8 in keratinocytes
Stich et al., Res Vet Sci 2011
:
Lipopolysaccharide was a more potent inducer of
IL-1ß and CXCL-8 than LTA or PG and LTA is a more potent inducer of CXCL-8 than PG. Based on these data, PAMPs from gram positive and negative bacteria
induce TNF, IL-1ß and
CXCL-8 production in feline whole blood
Blaine et al., J Orthop Res 2011
(Bursitis...) :
In cultured bursal synoviocytes,
SDF-1a gene expression and protein production are
stimulated by
IL-1ß
Kitahara et al., Inflamm Res 2012
(Arthritis, Rheumatoid) :
The mRNA expressions of CCL3, CCL4, and
CXCL8 were
up-regulated by
IL-1ß and down-regulated by tacrolimus
Chiang et al., BMC veterinary research 2012
(Dog Diseases...) :
Moreover, in P phase CTVT, while
IL-1ß and TGF-ß
had no obvious effect on
CXCL7 expression, IL-6 was found significantly to reduce CXCL7 expression in a dose dependent manner
Rafferty et al., Cell Immunol 2012
:
Suppressing ROCK with the Y27632 inhibitor suppressed
IL-1 stimulated Caco-2 cell
CXCL8/IL-8 and IEC-6 cell CCL2/MCP-1 secretion and mRNA levels