◀ Back to WNT6
SOX1 — WNT6
Text-mined interactions from Literome
Kormish et al., Dev Dyn 2010
(Neoplasms) :
In some contexts,
Wnt signaling also
regulates SOX expression resulting in feedback regulatory loops that fine-tune cellular responses to beta-catenin/TCF activity
Tsao et al., Hepatology 2012
(Carcinoma, Hepatocellular...) :
We used a T cell factor ( TCF ) -responsive luciferase reporter assay and western blot analysis to prove that
SOX1 could regulate TCF-responsive transcriptional activity and
inhibit the expression of
Wnt downstream genes
Wang et al., J Biol Chem 2013
(Breast Neoplasms...) :
Consistently,
SOX9 overexpression in BCa cell lines and transgenic SOX9 expression in breast epithelium
caused increased LRP6 and TCF4 expression and
Wnt/ß-catenin activation