Iliopoulos et al., PloS one 2008
(Inflammation...) :
Experimental validation revealed that miR-22 regulated PPARA and BMP7 expression and its inhibition blocked inflammatory and catabolic changes in osteoarthritic chondrocytes
Lee et al., Mol Cell Biol 2011
(Obesity...) :
Interestingly, miR-130 potently repressed PPAR? expression by targeting both the PPAR? mRNA coding and 3 ' untranslated regions
Ling et al., Clin Exp Pharmacol Physiol 2011
(MAP Kinase Signaling System) :
In contrast, anti-miR-375 increased ERK1/2 phosphorylation levels and inhibited mRNA expression of C/EBPa, PPAR?2 and aP2 in 3T3-L1 adipocyte, accompanied by decreased adipocyte differentiation
Reddi et al., Genes & cancer 2011
:
PPFP induced up-regulation of miR-122 expression was independent of its known dominant negative PPAR? activity