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ALB — SLC22A3

Text-mined interactions from Literome

Lee et al., American journal of physiology. Renal physiology 2011 : However, signaling pathways regulating both albumin induced EMT and ER stress are not precisely known ... Antioxidants, c-Src kinase inhibitor ( PP2 ), and mTOR inhibitor ( rapamycin ) suppressed the albumin induced EMT and ER stress ... Imatinib suppressed the albumin induced EMT and ER stress via inhibition of ROS and c-Src kinase
Xiao et al., Free radical research 2012 : However, the role of cordycepin on albumin induced EMT in renal tubular cells ( HK2 ) is unclear ... In this study, we investigated the effect of cordycepin on albumin induced EMT of HK2 cells and its mechanisms ... Results showed that albumin significantly induced EMT formation of HK-2 which associated with NADPH oxidase activation and intracellular ROS overproduction through increased Rac1 activity and expression of NOX4, p22phox and p47phox, while these effects were abolished in that pretreated with cordycepin ... In conclusion, cordycepin could ameliorate albumin induced EMT of HK2 cells by decreasing NADPH oxidase activity and inhibiting ROS production
Ibrini et al., Nephron. Experimental nephrology 2012 : A neutralising anti-TGF-ß1 antibody was used to analyse the role of TGF-ß1 in albumin induced EMT