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EGF — F2R

Text-mined interactions from Literome

Vesey et al., Kidney Int 2005 (Calcium Signaling...) : These responses which are dependent on its protease activity appear not to be mediated by PAR-1 activation, the autocrine action of thrombin induced TGF-beta1 secretion, MMP activation, or EGF receptor transactivation
Sekiguchi et al., Biochem Pharmacol 2007 : The PAR1 activating peptide (PAR1-AP) and thrombin increased PGE ( 2 ) release from RGM1 cells for 18h, an effect being suppressed by inhibitors of COX-1, COX-2, MEK, p38 MAP kinase (p38 MAPK), protein kinase C ( PKC ), Src and EGF receptor-tyrosine kinase (EGFR-TK) , but not JNK and matrix metalloproteinase ( MMP ) /a disintegrin and metalloproteinases ( ADAMs )