Gene interactions and pathways from curated databases and text-mining

◀ Back to IL13

IL13 — IL2RG

Text-mined interactions from Literome

Doucet et al., Eur J Immunol 2002 (Inflammation) : Here we show that in normal lung fibroblasts IL-4 and IL-13 induce the expression of the gamma c chain and its association with Janus kinase (JAK) 3, while lung myofibroblasts constitutively express a gamma c chain displaying a limited association with JAK3
Ginn et al., Hum Mutat 2004 (Genetic Diseases, X-Linked...) : Atypical phenotypes have also been described, but relatively little is known about the mechanisms by which the underlying mutations impair gammac dependent interleukin receptor signalling to produce these disease variants
He et al., J Immunol 1995 (Cell Transformation, Neoplastic) : The inability of m gamma or m gamma t expression to affect IL-13 induced proliferation by B9 indicates that gamma c does not obviously contribute to the IL-13R and does not function as the shared subunit of the IL-4R and IL-13R
Obiri et al., J Biol Chem 1995 : These data suggest that the interaction of IL-13 with IL-4R does not involve gamma c and IL-13R itself may be a novel subunit of the IL-4R
Obiri et al., J Biol Chem 1997 : To better understand the role of gammac in IL-13 binding and signaling, we have transfected a renal cell carcinoma cell line with gammac and examined IL-13 and IL-4 binding and signaling