Gene interactions and pathways from curated databases and text-mining

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HRAS — MVD

Pathways - manually collected, often from reviews:

  • OpenBEL Selventa BEL large corpus: HRAS → MVD (increases, HRAS Activity) Wadhwa et al., Biochem Biophys Res Commun 2003*
    Evidence: We have examined the effect of MPD-mot-2 interactions on the level and activity of p21(Ras) and its downstream effectors, p44 and p42 MAP kinases (ERK1/ERK2), in Ras-Raf pathway. An overexpression of mot-2 resulted in reduced level of Ras and phosphorylated ERK2.