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CCL2 — NFKBIA

Text-mined interactions from Literome

Weber et al., Blood 1999 : We found that overexpression of IkappaB-alpha in endothelial cells using a recombinant adenovirus prevented tumor necrosis factor-alpha (TNF-alpha) induced degradation of IkappaB-alpha and suppressed the upregulation of vascular cell adhesion molecule-1 ( VCAM-1 ), intercellular adhesion molecule-1 ( ICAM-1 ), and E-selectin mRNA and surface protein expression and the upregulation of transcripts for the chemokines monocyte chemoattractant protein 1 ( MCP-1 ) and growth related activity-alpha ( GRO-alpha ) by TNF-alpha
Wong et al., Am J Respir Cell Mol Biol 2005 : IL-25 could also activate the JNK, p38 MAPK, and NF-kappaB activities of eosinophils, while inhibitor of IkappaB-alpha phosphorylation ( BAY11-7082 ), JNK ( SP600125 ), and p38 MAPK ( SB203580 ) could suppress the release of IL-8, MIP-1alpha, MCP-1 , and IL-6
Matsuo et al., Kidney Int 2006 (Fibrosis) : Prednisolone increased I-kappaB-alpha expression and inhibited glucose/mannitol induced NF-kappaB DNA binding and MCP-1 expression without affecting PKC phosphorylation
Wang et al., Int J Food Microbiol 2010 : L. plantarum L2 inhibited MCP-1 secretion and mRNA expression via a NF-kappaB dependent pathway by interfering with IkappaBalpha degradation in TNF-alpha stimulated Caco-2 cells