Gene interactions and pathways from curated databases and text-mining

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CCL2 — NPPA

Text-mined interactions from Literome

Weber et al., J Leukoc Biol 2003 : ANP inhibits TNF-alpha induced endothelial MCP-1 expression -- involvement of p38 MAPK and MKP-1 ... Antisense experiments showed a requirement of MAPK phosphatase-1 (MKP-1) induction and therefore, inhibition of p38 MAPK in the ANP mediated inhibition of TNF-alpha induced expression of MCP-1
Moro et al., Diabetologia 2007 (Inflammation...) : ANP directly inhibited the secretion of IL-6 and monocyte chemoattractant protein-1 by macrophages