Gene interactions and pathways from curated databases and text-mining

◀ Back to IFNG

IFNG — PTK2

Text-mined interactions from Literome

Iwata et al., Jpn J Ophthalmol 2001 : Differential effects of protein tyrosine kinase inhibitors on interferon-gamma-induction of major histocompatibility complex class II and intercellular adhesion molecule-1 expression in human corneal epithelial cells ... Also, these PTK inhibitors prevented IFN-gamma-induction of MHC class II synthesis and surface expression ... In addition, it is suggested that the IFN-gamma-induction of MHC class II requires PTK activities not only in the primary JAK-signal transducers and activators of transcription ( STAT ) pathway but also in the subsequent pathway mediated by IFN-gamma induced intermediate proteins
Kobayashi et al., Vet Immunol Immunopathol 2005 : Moreover, the ConA induced IFN-gamma mRNA expression was partly prevented by genistein, a global PTK inhibitor, and PD-98059, an ERK inhibitor, respectively
Zhang et al., Zhonghua Zheng Xing Wai Ke Za Zhi 2005 (Cicatrix, Hypertrophic) : IFN-gamma activated transiently PTK ( P < 0.05 ) and increased proliferation and collagen synthesis of both fibroblast ( P < 0.05, at 30 min, 60 min )
Yoshida et al., Biochem Biophys Res Commun 1994 : The IFN-gamma-inducible IL-12 mRNA was blocked by two protein tyrosine kinase ( PTK ) inhibitors, genistein and herbimycin A, suggesting that PTK is involved in the IFN-gamma-inducible IL-12 mRNA expression