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IFNG — PTK2
Text-mined interactions from Literome
Iwata et al., Jpn J Ophthalmol 2001
:
Differential
effects of
protein tyrosine kinase inhibitors on
interferon-gamma-induction of major histocompatibility complex class II and intercellular adhesion molecule-1 expression in human corneal epithelial cells ... Also, these
PTK inhibitors
prevented IFN-gamma-induction of MHC class II synthesis and surface expression ... In addition, it is suggested that the
IFN-gamma-induction of MHC class II
requires PTK activities not only in the primary JAK-signal transducers and activators of transcription ( STAT ) pathway but also in the subsequent pathway mediated by IFN-gamma induced intermediate proteins
Kobayashi et al., Vet Immunol Immunopathol 2005
:
Moreover, the ConA induced
IFN-gamma mRNA expression was partly
prevented by genistein, a global
PTK inhibitor, and PD-98059, an ERK inhibitor, respectively
Zhang et al., Zhonghua Zheng Xing Wai Ke Za Zhi 2005
(Cicatrix, Hypertrophic) :
IFN-gamma activated transiently
PTK ( P < 0.05 ) and increased proliferation and collagen synthesis of both fibroblast ( P < 0.05, at 30 min, 60 min )
Yoshida et al., Biochem Biophys Res Commun 1994
:
The IFN-gamma-inducible IL-12 mRNA was blocked by two protein tyrosine kinase ( PTK ) inhibitors, genistein and herbimycin A, suggesting that
PTK is
involved in the
IFN-gamma-inducible IL-12 mRNA expression