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IGF2 — TYR
Text-mined interactions from Literome
Jones et al., Br J Cancer 2006
(Colonic Neoplasms) :
Insulin and
IGF-II promoted cell growth and pEGFR
Tyr845 , Tyr1068 and Tyr1173 activity and conversely, the insulin-like growth factor-1 receptor ( IGF-1R ) /InsR inhibitor ABDP ( 1 muM ) inhibited growth and reduced pEGFR activity at all three tyrosine residues
Nemoto et al., Neuropharmacology 2010
:
In SB216763 treated cells,
IGF-I induced
Tyr-autophosphorylation of IGF-I receptor was decreased by 36 %, compared to nontreated cells