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LPA — SMC6

Text-mined interactions from Literome

Adolfsson et al., Prostate 2002 (Prostatic Hyperplasia) : The proliferative effect of LPA on cultured human prostatic SMC from specimens obtained at trans-urethral resection of the prostate ( TURP ) because of BPH, was analyzed by [ 3H ] -thymidine and [ 35S ] -methionine incorporation ... LPA produced a dose dependent increase in BPH SMC , both regarding DNA- and protein-synthesis with EC50 values of 3 and 10 microM, respectively
Panchatcharam et al., Circ Res 2008 (Vascular Diseases) : These results identify a role for LPA1 and LPA2 in regulating SMC migratory responses in the context of vascular injury but suggest that additional LPA receptor subtypes are required for other LPA mediated effects in the vasculature