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EGF — MCL1

Text-mined interactions from Literome

Henson et al., J Cell Biochem 2003 : EGF increased the mRNA and protein levels of Mcl-1 ... In addition, up-regulation of Mcl-1 by EGF is mediated through AKT and NFkappaB activation since kinase inactive AKT and DeltaIkappaB effectively blocks this up-regulation ... Taken together, EGF signaling leads to increased Mcl-1 expression that is required for blockage of TRAIL induced apoptosis
Song et al., Cancer Biol Ther 2005 (Carcinoma, Non-Small-Cell Lung...) : We find that epidermal growth factor (EGF) can enhance Mcl-1 protein levels in an ERK dependent manner
Fleischer et al., Int J Oncol 2006 (Carcinoma, Hepatocellular...) : Furthermore, the hepatocyte growth factor and epidermal growth factor induced Mcl-1 expression in an Akt- and ERK dependent manner
Schulze-Bergkamen et al., World J Gastroenterol 2008 (Adenocarcinoma...) : EGF treatment clearly induced Bcl-x ( L ) and Mcl-1 expression in CRC cells