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JUN — SPHK1

Text-mined interactions from Literome

Paugh et al., J Biol Chem 2009 (Glioblastoma...) : The IL-1 induced SphK1 up-regulation can be blocked by the inhibition of JNK, the overexpression of the dominant negative c-Jun ( TAM67 ), and the down-regulation of c-Jun expression by small interference RNA
Lan et al., Mol Endocrinol 2011 (Diabetes Mellitus, Experimental...) : Finally, by inhibiting SphK1 activity, both N, N-dimethylsphingosine and SphK ( G82D ) markedly attenuated the HG-induced AP-1 activity
Su et al., J Biol Chem 1994 : Furthermore, an inhibitor of sphingosine kinase , DL-threo-dihydrosphingosine, which inhibits sphingosine induced DNA synthesis and the formation of sphingosine 1-phosphate, also inhibited sphingosine stimulated AP-1 DNA binding activity