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TLR2 — VEGFA

Text-mined interactions from Literome

Varoga et al., J Pathol 2006 (Arthritis, Infectious...) : TLR-2 mediated induction of vascular endothelial growth factor ( VEGF ) in cartilage in septic joint disease ... The findings demonstrate the expression of Toll-like receptors on mesenchymal articular chondrocytes and reveal TLR-2 mediated VEGF induction in human chondrocytes after Gram positive bacterial sensing
Cho et al., Immunol Lett 2007 (Arthritis, Rheumatoid) : Thus, TLR-2 activation in RA FLS by microbial constituents could be involved in the induction of VEGF and IL-8 and thereby promote inflammation either directly or via angiogenesis
Koff et al., Am J Physiol Lung Cell Mol Physiol 2008 : We conclude that multiple TLR ligands induce airway epithelial cell production of IL-8 and VEGF via a Duox1 -- > ROS -- > TACE -- > TGF-alpha -- > EGFR phosphorylation pathway
Kawamura et al., Experimental biology and medicine (Maywood, N.J.) 2008 : The FFAs induced VEGF expression was mostly mediated by TLR2
Xie et al., Biochem Biophys Res Commun 2009 (Breast Neoplasms...) : TLR2 activation increased IL-6, TGF-beta, VEGF and MMP9 secretion, which are associated with TLR2-NF-kappaB signaling
Regueira et al., Liver Int 2009 : TNF-alpha and TLR-2 , -3 and -4 agonists induced the expression of vascular endothelial growth factor , which was partially abolished by the blockage of HIF-1 alpha with CTM
Grinberg et al., Am J Pathol 2009 (Inflammation) : This switch involves induction of A ( 2A ) Rs by TLR agonists, down-regulation of tumor necrosis factor alpha (TNFalpha) and interleukin-12, and up-regulation of vascular endothelial growth factor ( VEGF ) and interleukin-10 expression
Abarbanell et al., Am J Physiol Heart Circ Physiol 2010 (Myocardial Reperfusion Injury) : However, it is unknown whether TLR2 activation on the MSCs affects MSC mediated myocardial recovery and VEGF production
Spirig et al., PloS one 2010 : In addition, we could show that TLR stimulation resulted in an increase of HIF-1alpha controlled VEGF secretion
Paolillo et al., Int J Immunopathol Pharmacol 2012 : Induction of VEGF and MMP-9 expression by toll-like receptor 2/4 in human endothelial cells infected with Chlamydia pneumoniae
Juárez-Verdayes et al., Graefes Arch Clin Exp Ophthalmol 2013 : Peptidoglycan and muramyl dipeptide from Staphylococcus aureus induce the expression of VEGF-A in human limbal fibroblasts with the participation of TLR2-NF?B and NOD2-EGFR