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IFNAR1 — PKD2
Text-mined interactions from Literome
Zheng et al., Mol Cell Biol 2011
:
Expression and kinase activity of
PKD2 are
required for the ligand-inducible stimulation of
IFNAR1 ubiquitination and endocytosis and for accelerated proteolytic turnover of IFNAR1
Zheng et al., J Biol Chem 2011
:
Tyrosine phosphorylation of
PKD2 is
required for IFNa stimulated activation of this kinase as well as for efficient serine phosphorylation and degradation of
IFNAR1 and ensuing restriction of the extent of cellular responses to IFNa