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CFTR — GNB2L1

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: GNB2L1 — CFTR (physical association, affinity chromatography technology) Wang et al., Cell 2006
• IRef Intact Interaction: Complex of 26 proteins (association, anti bait coimmunoprecipitation) Wang et al., Cell 2006

Text-mined interactions from Literome

Liedtke et al., Am J Physiol Cell Physiol 2004 : CFTR activation by cAMP generating agent is not affected by loss of RACK1-NHERF1 interaction
Auerbach et al., Am J Physiol Cell Physiol 2007 : Role of the scaffold protein RACK1 in apical expression of CFTR ... Downregulation of RACK1 using double stranded silencing RNA reduced the amount of RACK1 by 77.5 % and apical expression of biotinylated CFTR by 87.4 %
Smith et al., Am J Physiol Cell Physiol 2013 : The scaffold protein receptor for activated C kinase 1 ( RACK1 ) also stabilizes CFTR surface expression ; however, RACK1 does not interact directly with CFTR and its mechanism of action is unknown ... Disruption of the RACK1-FlnA interaction causes a reduction in CFTR surface levels