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AHSA1 — ANGPT2
Text-mined interactions from Literome
Reddy et al., American journal of physiology. Renal physiology 2002
(Diabetic Nephropathies...) :
ANG II and 12 ( S ) -HETE
led to activation of
p38 ( MAPK ) and its target transcription factor cAMP-responsive element binding protein ( CREB )
Natarajan et al., Endocrine 2002
:
However, both
ANG II and 12-HETE
led to significant dose dependent increases in
p38 MAPK activity with peak effects at 5 min
Chan et al., Circ Res 2005
:
Functionally,
Ang II-elicited pressor response in the RVLM was
attenuated by DPI, tempol, or a
p38 MAPK inhibitor, SB203580
Pham et al., J Cell Physiol 2008
:
The
p38 ( MAPK ) selective inhibitor, SB202190, but not the MEK selective inhibitor, PD98059, or the EGFR kinase inhibitor, AG1478,
inhibited Ang II-dependent COX-2 expression and CREB phosphorylation
Marsh et al., Amino Acids 2011
(Diabetes Mellitus, Type 2...) :
ANG II and PE significantly
increased levels of ANP and a-actin and phosphorylation of
p38 and ERK in the non-diabetic but not in the diabetic group ; phosphorylation of Akt was unchanged irrespective of group or treatment
Paravicini et al., Journal of the American Society of Hypertension : JASH 2012
(Disease Models, Animal...) :
We examined
effects of stretch and
Ang II on activation of
p38MAPK in vascular smooth muscle cells ( VSMC ) from WKY and SHR