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BTRC — RELA
Pathways - manually collected, often from reviews:
-
NCI Pathway Database Signaling events mediated by HDAC Class I:
NF kappa B/RelA/I kappa B alpha complex (NFKBIA-RELA)
→
beta TrCP1/SCF ubiquitin ligase complex complex (BTRC)
(modification, collaborate)
-
NCI Pathway Database Canonical NF-kappaB pathway:
beta TrCP1/SCF ubiquitin ligase complex complex (BTRC)
→
NF kappa B1 p50/RelA/I kappa B alpha complex (NFKB1-NFKBIA-RELA)
(modification, activates)
-
NCI Pathway Database Canonical NF-kappaB pathway:
beta TrCP1/SCF ubiquitin ligase complex complex (BTRC)
→
NF kappa B1 p50/RelA complex (NFKB1-RELA)
(modification, activates)
-
Reactome Reaction:
BTRC
→
RELA
(indirect_complex)
Suzuki et al., Biochem Biophys Res Commun 1999, Tan et al., Mol Cell 1999, Fuchs et al., Oncogene 1999, Wu et al., J Biol Chem 1999, Yaron et al., Nature 1998, Winston et al., Genes Dev 1999
-
Reactome Reaction:
BTRC
→
RELA
(reaction)
Suzuki et al., Biochem Biophys Res Commun 1999, Tan et al., Mol Cell 1999, Fuchs et al., Oncogene 1999, Wu et al., J Biol Chem 1999, Yaron et al., Nature 1998, Winston et al., Genes Dev 1999
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
-
IRef Bind Interaction:
Complex of 25 proteins
Bouwmeester et al., Nat Cell Biol 2004
-
IRef Bind Interaction:
Complex of 11 proteins
Bouwmeester et al., Nat Cell Biol 2004
-
IRef Biogrid Interaction:
BTRC
—
RELA
(physical association, affinity chromatography technology)
Spencer et al., Genes Dev 1999*
-
MIPS CORUM TNF-alpha/NF-kappa B signaling complex (CHUK, BTRC, NFKB2, PPP6C, REL, CUL1, IKBKE, SAPS2, SAPS1, ANKRD28, RELA, SKP1):
TNF-alpha/NF-kappa B signaling complex (CHUK, BTRC, NFKB2, PPP6C, REL, CUL1, IKBKE, SAPS2, SAPS1, ANKRD28, RELA, SKP1) complex (ANKRD28-BTRC-CHUK-CUL1-IKBKE-NFKB2-PPP6C-REL-RELA-PPP6R1-PPP6R2-SKP1)
Bouwmeester et al., Nat Cell Biol 2004
-
IRef Corum Interaction:
Complex of 13 proteins
(association, tandem affinity purification)
Bouwmeester et al., Nat Cell Biol 2004
-
IRef Hprd Interaction:
RELA
—
BTRC
(in vitro)
Spencer et al., Genes Dev 1999*
-
IRef Hprd Interaction:
RELA
—
BTRC
(in vivo)
Spencer et al., Genes Dev 1999*
-
IRef Ophid Interaction:
BTRC
—
RELA
(aggregation, confirmational text mining)
Spencer et al., Genes Dev 1999*
-
IRef Ophid Interaction:
BTRC
—
RELA
(aggregation, interologs mapping)
Brown et al., Bioinformatics 2005
Text-mined interactions from Literome
Spiegelman et al., J Biol Chem 2001
:
Induction of
beta-transducin repeat containing protein by JNK signaling and its
role in the activation of
NF-kappaB
Wang et al., Arterioscler Thromb Vasc Biol 2004
:
The
role of [
beta]-transducin repeat containing protein ( [ beta ] -TrCP ) in the regulation of
NF-[kappa]B in vascular smooth muscle cells
Wong et al., Allergy 2006
:
The induction of RANTES by SCF or TNF-alpha was mediated by ERK and
NF-kappaB , respectively, and
SCF induced MIP-1beta release was mediated by ERK