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ESR1 — MED12

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: ESR1 — MED12 (direct interaction, pull down) Kang et al., Proc Natl Acad Sci U S A 2002
• IRef Biogrid Interaction: ESR1 — MED12 (physical association, affinity chromatography technology) Kang et al., Proc Natl Acad Sci U S A 2002
• MIPS CORUM TFTC-type histone acetyl transferase complex: TFTC-type histone acetyl transferase complex complex (ESR1-KAT2A-MED1-MED12-MED13-MED14-MED16-MED17-MED23-MED24-TRRAP) Yanagisawa et al., Mol Cell 2002
• IRef Corum Interaction: Complex of 34 proteins (association, cosedimentation through density gradient) Yanagisawa et al., Mol Cell 2002

Text-mined interactions from Literome

Acevedo et al., Mol Cell Biol 2003 : We have used a biochemical approach, including an in vitro chromatin assembly and transcription system, to examine the functional role for Mediator in the transcriptional activity of estrogen receptor alpha (ERalpha) with chromatin templates, as well as functional interplay between Mediator and p300/CBP during ERalpha dependent transcription ... Using three different approaches to functionally inactivate Mediator ( immunoneutralization, immunodepletion, and inhibitory polypeptides ), we find that Mediator is required for maximal transcriptional activation by ligand activated ERalpha
Leite et al., J Neuroendocrinol 2008 : ERalpha expression in TH-ir neurones increased at 14 and 16 h in the rostral-ARC and dorsomedial-ARC, 14 h in the caudal-ARC and 16 h in the VMPO, whereas it was unaltered in the ventrolateral-ARC, periventricular and AVPe