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APOB — MPO

Text-mined interactions from Literome

Carr et al., J Biol Chem 2001 : Since MPO and MPO derived HOCl, as well as reactive nitrogen species, have been implicated in the pathogenesis of atherosclerosis through oxidative modification of low density lipoprotein (LDL), we investigated the effects of physiological concentrations of nitrite ( 12.5-200 microm ) on MPO mediated modification of LDL in the absence and presence of physiological chloride concentrations
Raveh et al., Free Radic Biol Med 2001 : These studies revealed that oxidation of LDL induced either by AAPH or MPO is inhibited by HDL under all the studied conditions, whereas copper induced oxidation of LDL is inhibited by HDL at low copper/lipoprotein ratio but accelerated by HDL at high copper/lipoprotein ratio
Sies et al., Am J Clin Nutr 2005 : This review provides a survey of our research on the effects of cocoa polyphenols on leukotriene and nitric oxide ( NO ) metabolism and on myeloperoxidase induced modification of LDL ... Micromolar concentrations of ( - ) -epicatechin or other flavonoids were found to suppress lipid peroxidation in LDL induced by myeloperoxidase in the presence of physiologically relevant concentrations of nitrite, an NO metabolite
Van Antwerpen et al., Biochem Biophys Res Commun 2005 : The key role of myeloperoxidase (MPO) in this process has been documented and the enzyme has been involved in the oxidative modification of apolipoprotein B-100 in the intima and at the surface of endothelial cells