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CRH — S100A12
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Dhillo et al., Endocrinology 2003
:
CGRP ( 100 nM )
stimulated the release of alpha-melanocyte stimulating hormone, cocaine- and amphetamine related transcript,
corticotropin releasing hormone , and arginine vasopressin from hypothalamic explants to 127 +/- 19 %, 148 +/- 10 %, 158 +/- 17 %, and 198 +/- 21 % of basal levels, respectively ( P < 0.05 vs. basal ), but did not alter the release of either neuropeptide Y or agouti related protein
Bowe et al., Stress 2008
:
The aims of the present study were to examine the role of CRH-R1 and CRH-R2 in CGRP induced suppression of LH pulses, and to investigate the
effects of
CGRP on
CRH expression in the paraventricular nucleus ( PVN ) and central nucleus of the amygdala (CeA), which have prominent CRH neurone populations that receive dense CGRP innervations ...
CGRP increased the
CRH mRNA expression in PVN and CeA
Sink et al., Behav Brain Res 2013
:
Anxiogenic effects of
CGRP within the BNST may be
mediated by
CRF acting at BNST CRFR1 receptors ... Together, these results suggest that the anxiogenic effects of intra-BNST
CGRP may be
mediated by
CRF from BNST neurons acting at local CRFR1 receptors