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ID1 — SRC

Text-mined interactions from Literome

Gautschi et al., Cancer Res 2008 (Neoplasm Invasiveness...) : Regulation of Id1 expression by SRC : implications for targeting of the bone morphogenetic protein pathway in cancer ... PP2, AZD0530, and dominant negative Src abrogated Id1 promoter activity, which was induced by constitutively active Src ... Src was also required for bone morphogenetic protein-2 (BMP-2) induced Id1 expression and promoter activity, was moderately activated by BMP-2, and complexed with Smad1/5
Rothschild et al., Lung Cancer 2011 (Carcinoma, Non-Small-Cell Lung) : As shown recently, ID1 is positively regulated by the tyrosine kinase SRC in lung carcinoma cell lines and with that appears as a potential new therapeutic target in non-small cell carcinoma ( NSCLC )