Chiu et al., Arterioscler Thromb Vasc Biol 2005
(Vasculitis) :
Shear stress inhibited the SMC coculture induced NF-kappaB activation in ECs and monocytic THP-1 cell adhesion to ECs
Ibe et al., Cell Prolif 2008
(Anoxia) :
SMC-PV proliferated more than SMC-PA and PAF plus hypoxia augmented NF-kappaB protein expression
Bai et al., Mol Cancer Ther 2009
(Neoplasms) :
Conversely, SMC3 induced NF-kappaB activation was found to be mediated by autocrine TNF because this effect of SMC3 was effectively inhibited when TNF was blocked with either a TNF neutralizing antibody or TNF small interfering RNA
Bourcier et al., J Biol Chem 1997
(Arteriosclerosis) :
SMC cultured under serum-free conditions displayed little NFkappaB activity, but addition of serum or platelet derived growth factor did activate NFkappaB Lavie et al., J Biol Chem 1999
:
Since VCAM-1 expression appears developmentally regulated and cytokine-inducible in smooth muscle cells ( SMCs ), we have studied the role of NF-kappaB in differentiated SMC VCAM-1 expression