◀ Back to MAPK14
MAPK14 — TGFB3
Text-mined interactions from Literome
Johansson et al., J Cell Sci 2000
(Carcinoma, Squamous Cell) :
In addition,
transforming growth factor- ( beta ) ( TGF- ( beta )
activated p38
MAPK in both cell lines, and ERK2 in A-5 cells
Lu et al., Endocrinology 2001
:
In addition, PKC and
MAPK inhibitors
had no effect on the induction of
TGFbeta3 promoter activity by the SERM EM-652 ... These results indicate that induction of the
TGFbeta3 promoter by the E(2)/ERalpha complex
requires the concomitant activation of PKC and
MAPK signaling and provide a novel framework for the design of more effective estrogen based therapeutic strategies
Westermarck et al., Mol Cell Biol 2001
(MAP Kinase Signaling System) :
In contrast, activation of stress activated c-Jun N-terminal kinase and p38 pathways by expression of constitutively active mutants of Rac,
transforming growth factor beta activated kinase 1 ( TAK1 ),
MAPK kinase 3 ( MKK3 ) , or MKK6 or by treatment with arsenite or anisomycin did not alone markedly enhance MMP-1 promoter activity
Bhowmick et al., J Biol Chem 2001
:
Integrin beta 1 signaling is necessary for
transforming growth factor-beta activation of
p38MAPK and epithelial plasticity
Sato et al., J Invest Dermatol 2002
(Scleroderma, Systemic) :
Role of p38
MAPK in
transforming growth factor beta stimulation of collagen production by scleroderma and healthy dermal fibroblasts ... In conclusion, this study demonstrates a costimulatory
role for p38
MAPK in
transforming growth factor beta induction of the collagen type I gene
Suzuki et al., Clin Exp Nephrol 2004
:
Role of
mitogen activated protein kinase in the regulation of
transforming growth factor-beta induced fibronectin accumulation in cultured renal interstitial fibroblasts
Roux et al., J Biol Chem 2005
(Edema) :
The inhibitory effect of IL-1beta on alpha ENaC expression was mediated by the activation of p38
MAPK in both rat and human ATII cells and was
independent of the activation of alpha v beta6 integrin and
transforming growth factor-beta
Leung et al., Nephrol Dial Transplant 2005
:
The GDP induced VEGF and
transforming growth factor ( TGF ) -beta synthesis in HPMC was partially
reduced by either the p42/p44
MAPK inhibitor ( PD98059 ) or the PKC inhibitor ( staurosporine )
Chaturvedi et al., J Pharmacol Exp Ther 2005
(MAP Kinase Signaling System) :
Pretreatment of FS cells with a mitogen activated protein kinase kinase 1/2 inhibitor or with a protein kinase C ( PKC ) inhibitor suppressed the
TGF-beta3 and ethanol
actions on
MAPK p44/42 activation and bFGF release ... Furthermore, the
MAPK p44/42
activation by
TGF-beta3 and ethanol was blocked by overexpression of Ras N17, a dominant negative mutant of Ras p21
Gaide Chevronnay et al., Endocrinology 2008
:
In presence of ovarian steroids,
MAPK inhibitors ( p38 and ERK pathways )
stimulated TGF-beta3 but inhibited TGF-beta2 expression ... The opposite
regulation of
TGF-beta2 and -beta3 by cAMP and
MAPK could account for their distinct expression in vivo
Krug et al., Hypertension 2010
:
MR blockade and extracellular signal regulated kinase 1/2
mitogen activated protein kinase inhibition
prevent age associated increases of
transforming growth factor-beta , intercellular adhesion molecule 1, and procollagen 1
Leenders et al., J Biol Chem 2010
(Hypertrophy, Left Ventricular) :
We show that
transforming growth factor-beta mediated
activation of p38
MAPK is necessary and sufficient to decrease KLF15 expression