UCSC Genome Browser Gene Interaction Graph

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Gene interactions and pathways from curated databases and text-mining

◀ Back to BMPR2

BMPR2 — SOSTDC1

Pathways - manually collected, often from reviews:

NCI Pathway Database BMP receptor signaling: USAG1 (SOSTDC1) → BMP2-4/BMPR2/BMPR1A-1B/RGM complex (BMP4_BMP2-BMPR2-BMPR1A_BMPR1B-RGMB_RGMA_HFE2) (modification, collaborate)
Onichtchouk et al., Nature 1999, Nohe et al., J Biol Chem 2002, Yanagita et al., Biochem Biophys Res Commun 2004, Samad et al., J Biol Chem 2005, Babitt et al., J Biol Chem 2005, Babitt et al., Nat Genet 2006, Rosenzweig et al., Proc Natl Acad Sci U S A 1995, Nohno et al., J Biol Chem 1995, Liu et al., Mol Cell Biol 1995, Suzuki et al., Proc Natl Acad Sci U S A 1994, ten Dijke et al., J Biol Chem 1994, Koenig et al., Mol Cell Biol 1994
Evidence: mutant phenotype, physical interaction, other species
NCI Pathway Database BMP receptor signaling: USAG1 (SOSTDC1) → BMPR2 (homodimer) complex (BMPR2) (modification, collaborate)
Onichtchouk et al., Nature 1999, Nohe et al., J Biol Chem 2002, Yanagita et al., Biochem Biophys Res Commun 2004, Samad et al., J Biol Chem 2005, Babitt et al., J Biol Chem 2005, Babitt et al., Nat Genet 2006, Rosenzweig et al., Proc Natl Acad Sci U S A 1995, Nohno et al., J Biol Chem 1995, Liu et al., Mol Cell Biol 1995, Suzuki et al., Proc Natl Acad Sci U S A 1994, ten Dijke et al., J Biol Chem 1994, Koenig et al., Mol Cell Biol 1994
Evidence: mutant phenotype, physical interaction, other species
NCI Pathway Database BMP receptor signaling: BMP2-4/BMPR2/BMPR1A-1B/RGM complex (BMP4_BMP2-BMPR2-BMPR1A_BMPR1B-RGMB_RGMA_HFE2) → BMP2-4/USAG1 complex (BMP4_BMP2-SOSTDC1) (modification, collaborate)
Onichtchouk et al., Nature 1999, Nohe et al., J Biol Chem 2002, Yanagita et al., Biochem Biophys Res Commun 2004, Samad et al., J Biol Chem 2005, Babitt et al., J Biol Chem 2005, Babitt et al., Nat Genet 2006, Rosenzweig et al., Proc Natl Acad Sci U S A 1995, Nohno et al., J Biol Chem 1995, Liu et al., Mol Cell Biol 1995, Suzuki et al., Proc Natl Acad Sci U S A 1994, ten Dijke et al., J Biol Chem 1994, Koenig et al., Mol Cell Biol 1994
Evidence: mutant phenotype, physical interaction, other species
NCI Pathway Database BMP receptor signaling: BMPR2 (homodimer) complex (BMPR2) → BMP2-4/USAG1 complex (BMP4_BMP2-SOSTDC1) (modification, collaborate)
Onichtchouk et al., Nature 1999, Nohe et al., J Biol Chem 2002, Yanagita et al., Biochem Biophys Res Commun 2004, Samad et al., J Biol Chem 2005, Babitt et al., J Biol Chem 2005, Babitt et al., Nat Genet 2006, Rosenzweig et al., Proc Natl Acad Sci U S A 1995, Nohno et al., J Biol Chem 1995, Liu et al., Mol Cell Biol 1995, Suzuki et al., Proc Natl Acad Sci U S A 1994, ten Dijke et al., J Biol Chem 1994, Koenig et al., Mol Cell Biol 1994
Evidence: mutant phenotype, physical interaction, other species
NCI Pathway Database BMP receptor signaling: BMP7/USAG1 complex (BMP7-SOSTDC1) → BMP7/BMPR2/BMPR1A-1B complex (BMP7-BMPR2-BMPR1A_BMPR1B) (modification, collaborate)
Onichtchouk et al., Nature 1999, Yanagita et al., Biochem Biophys Res Commun 2004, Rosenzweig et al., Proc Natl Acad Sci U S A 1995, Liu et al., Mol Cell Biol 1995, ten Dijke et al., J Biol Chem 1994
Evidence: physical interaction
NCI Pathway Database BMP receptor signaling: BMP7/USAG1 complex (BMP7-SOSTDC1) → BMPR2 (homodimer) complex (BMPR2) (modification, collaborate)
Onichtchouk et al., Nature 1999, Yanagita et al., Biochem Biophys Res Commun 2004, Rosenzweig et al., Proc Natl Acad Sci U S A 1995, Liu et al., Mol Cell Biol 1995, ten Dijke et al., J Biol Chem 1994
Evidence: physical interaction
NCI Pathway Database BMP receptor signaling: USAG1 (SOSTDC1) → BMP7/BMPR2/BMPR1A-1B complex (BMP7-BMPR2-BMPR1A_BMPR1B) (modification, collaborate)
Onichtchouk et al., Nature 1999, Yanagita et al., Biochem Biophys Res Commun 2004, Rosenzweig et al., Proc Natl Acad Sci U S A 1995, Liu et al., Mol Cell Biol 1995, ten Dijke et al., J Biol Chem 1994
Evidence: physical interaction
NCI Pathway Database BMP receptor signaling: USAG1 (SOSTDC1) → BMPR2 (homodimer) complex (BMPR2) (modification, collaborate)
Onichtchouk et al., Nature 1999, Yanagita et al., Biochem Biophys Res Commun 2004, Rosenzweig et al., Proc Natl Acad Sci U S A 1995, Liu et al., Mol Cell Biol 1995, ten Dijke et al., J Biol Chem 1994
Evidence: physical interaction