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NOS1 — PI3

Text-mined interactions from Literome

Liu et al., Circulation 2003 (MAP Kinase Signaling System) : In endothelial cells, aldosterone caused a phosphatidylinositol 3-kinase (PI3K) dependent increase in nitric oxide synthase activity as well as PI3K dependent activation of extracellular signal regulated kinase 1/2 and p70 S6 kinase
Kasina et al., Nitric Oxide 2006 : A decrease in the level of nitroprofilin in PDBu treated platelets in the presence of inducible nitric oxide synthase inhibitor, 1400W, was observed suggesting that profilin nitration is mediated by PI 3-kinase dependent activation of inducible nitric oxide synthase
Casanello et al., Curr Vasc Pharmacol 2007 (Diabetes, Gestational...) : Modulation of ENTs, CATs, and NOS expression and activity in endothelium involves protein kinase C ( PKC ), mitogen activated protein kinases p42 and p44 ( p42/44(mapk) ), calcium, and phosphatidyl inositol 3 kinase (PI3k) , among others
Downey et al., Ann N Y Acad Sci 2008 (Myocardial Ischemia) : PI3-kinase causes extracellular signal regulated kinase ( ERK ) -dependent activation of endothelial nitric oxide synthase
Cheng et al., Br J Pharmacol 2012 (Hypotension) : Effects of a selective antagonist of Y ( 1 ) receptors, a PKC inhibitor, a PI3 kinase inhibitor, a NOS inhibitor , an endothelial NOS (eNOS)-selective inhibitor, a neuronal NOS (nNOS)-specific inhibitor or a MAPK inhibitor, on responses to microinjection of NPY into the NTS of Wistar-Kyoto rats were studied to determine the underlying mechanisms
Xu et al., Int J Mol Med 2013 : In another set of cultures, the cells were co-incubated with RTB and the tyrosine kinase inhibitor, genistein, the phosphatidylinositol 3-kinase (PI3K) inhibitor, LY294002, the p42/44 inhibitor, PD98059, the p38 inhibitor, SB203580, the JNK inhibitor, SP600125, the protein kinase C ( PKC ) inhibitor, staurosporine, the JAK2 inhibitor, tyrphostin ( AG490 ), or the NOS inhibitor , L-NMMA