Gene interactions and pathways from curated databases and text-mining

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E2F4 — EGF

Text-mined interactions from Literome

Hanada et al., Mol Carcinog 2006 : Promoter mutagenesis studies showed that EGF induced activation of B-Myb promoter required both E2F and EGFR target sites
Loomis et al., Cancer Res 2007 : We observed that C/EBPalpha blocked Ras induced and epidermal growth factor induced E2F activity in keratinocytes and also blocked Ras induced cell transformation and cell cycle progression
Kitano et al., Am J Physiol 1998 : We examined epidermal growth factor (EGF)- and epinephrine stimulated mitogen activated protein kinase kinase ( MEK) 1 and MEK2 activities, DNA polymerase alpha activity, and EGF stimulated E2F DNA binding activity in primary cultured hepatocytes from 6- and 24-mo-old rats ... EGF stimulated E2F ( a transcription factor that regulates expression of the DNA polymerase alpha gene ) binding to DNA was reduced with age