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CALM3 — IL2
Text-mined interactions from Literome
Ito et al., J Biol Chem 1991
:
These results indicate that
calmodulin is
required for the
interleukin 1-enhanced synthesis of TIMP but it is a suppressor for the synthesis of proMMPs-1 and -3
Sugiyama et al., Clin Exp Immunol 2007
:
Because dendritic cells (DCs) orchestrate immune responses, we examined the in vitro
effects of
clarithromycin (CAM) , azithromycin ( AZM ) and midecamycin ( MDM ) on the expression of co-stimulatory molecules and production of cytokines
[interleukin (IL)-10, IL-6, interferon (IFN)-gamma, IL-12p40, tumour necrosis factor (TNF)-alpha ] of murine bone marrow derived DCs by lipopolysaccharide (LPS) stimulation
Yokota et al., Mediators Inflamm 2012
(Respiratory Syncytial Virus Infections) :
Clarithromycin (CAM) , which is an antimicrobial agent and is also known as an immunomodulator, significantly
suppressed RSV induced production of interleukin-6,
interleukin-8 , and regulated on activation, normal T-cell expressed and secreted ( RANTES )
Ojima et al., Biochim Biophys Acta 1989
:
Calmodulin regulates the
interleukin 1-induced procollagenase production in human uterine cervical fibroblasts
Kawakami et al., Microbiol Immunol 1988
:
The
IL2 production was
reduced by inhibitors of
calmodulin and protein kinase C
Hama et al., J Exp Med 1995
:
The inhibitory
effect of
CaM-K II on
IL-2 promoter was associated with decreased transcription of its AP-1 and NF-AT transactivating pathways ... When both mutants were used in combination, gamma
B*CaM-K inhibited the induction of the
IL-2 promoter by delta CaM-AI
Wölfler et al., Life Sci 1998
:
Since melatonin has been suggested as a physiological antagonist to calmodulin in certain cell types, we investigated effects of melatonin on
calmodulin dependent
IL-2 production and proliferation of activated T-lymphocytes