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MYC — NOTCH4
Text-mined interactions from Literome
Rao et al., Mol Cell Biol 2003
:
c-Myc expression was also maintained in low serum, indicating that
Notch 's
effects on
c-Myc are not specific to TGF-beta
Riz et al., Molecular cancer 2010
(Precursor T-Cell Lymphoblastic Leukemia-Lymphoma) :
We found that TLX1 and
NOTCH synergistically
regulate transcription in T-ALL, at least in part via the sharing of a TLE corepressor and by augmenting expression of
MYC
Blackburn et al., Leukemia 2012
(Cell Transformation, Neoplastic...) :
Here, we utilized a zebrafish transgenic model of T-ALL, where
Notch does not
induce Myc transcription, to identify a novel Notch gene expression signature that is also found in human T-ALL and is regulated independently of Myc