Gene interactions and pathways from curated databases and text-mining

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CDC45 — CDK4

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Bruck et al., J Biol Chem 2011 : Sld3 binds tightly to Cdc45 in the presence or absence of cyclin dependent kinase activity
Jallepalli et al., Genes Dev 1996 : Rum1 and Cdc18 link inhibition of cyclin dependent kinase to the initiation of DNA replication in Schizosaccharomyces pombe