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MAP3K5 — MAPK8IP3

Pathways - manually collected, often from reviews:

• OpenBEL Selventa BEL large corpus: MAPK8IP3 → MAP3K5 (increases, MAPK8IP3 Activity) Matsuura et al., J Biol Chem 2002*
  Evidence: Furthermore, ASK1-dependent phosphorylation was required for JSAP1 to recruit and thereby activate JNK in response to H(2)O(2).
• OpenBEL Selventa BEL large corpus: MAP3K5 → MAPK8IP3 (increases, MAPK8IP3 Activity)
  Evidence: Glucose deprivation rapidly increases the interaction between ASK1 and JIP3, and the consequently activated ASK1 phosphorylates SEK1 on the Thr-261 residue.

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: MAP3K5 — MAPK8IP3 (physical association, affinity chromatography technology) Song et al., J Cell Biochem 2004*
• IRef Biogrid Interaction: MAP3K5 — MAPK8IP3 (physical association, affinity chromatography technology) Matsuura et al., J Biol Chem 2002*
• IRef Biogrid Interaction: MAP3K5 — MAPK8IP3 (direct interaction, enzymatic study) Matsuura et al., J Biol Chem 2002*
• IRef Hprd Interaction: MAP3K5 — MAPK8IP3 (in vitro) Matsuura et al., J Biol Chem 2002*
• IRef Hprd Interaction: MAP3K5 — MAPK8IP3 (in vivo) Matsuura et al., J Biol Chem 2002*