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EGF — ERCC1
Text-mined interactions from Literome
Yacoub et al., Radiat Res 2003
(Adenocarcinoma...) :
Although the EGFR inhibitor tyrphostin ( AG-1478 ) and the MEK inhibitor PD90859 both attenuated
EGF induced levels of the
ERCC1 and XRCC1 protein, PD98059 blocked the induction of ERCC1 and XRCC1 by radiation more effectively in both cell lines
Andrieux et al., Cancer Res 2007
(Carcinoma, Hepatocellular...) :
GATA-1 is essential in
EGF mediated induction of nucleotide excision repair activity and
ERCC1 expression through ERK2 in human hepatoma cells ... Moreover,
EGF mediated activation of
ERCC1 was specifically inhibited by either the addition of U0126, a MEK/ERK inhibitor or small interfering RNA mediated knockdown of ERK2
Wang et al., Anticancer Drugs 2013
(Adenocarcinoma...) :
In contrast,
epidermal growth factor induced increase in
ERCC1 protein levels was shown to rescue cell viability upon 8-c treatment