◀ Back to RAC1
DOCK6 — RAC1
Pathways - manually collected, often from reviews:
-
NCI Pathway Database Regulation of RAC1 activity:
RAC1/GDP complex (RAC1)
→
DOCK6 (DOCK6)
(modification, collaborate)
Miyamoto et al., Exp Cell Res 2007
Evidence: assay
-
Reactome Reaction:
DOCK6
→
RAC1
(reaction)
Brugnera et al., Nat Cell Biol 2002, Meller et al., J Biol Chem 2004, Nishikimi et al., FEBS Lett 2005, Hiramoto et al., Exp Cell Res 2006*, Miyamoto et al., Exp Cell Res 2007
-
Reactome Reaction:
DOCK6
→
RAC1
(direct_complex)
Brugnera et al., Nat Cell Biol 2002, Meller et al., J Biol Chem 2004, Nishikimi et al., FEBS Lett 2005, Hiramoto et al., Exp Cell Res 2006*, Miyamoto et al., Exp Cell Res 2007
Text-mined interactions from Literome
Namekata et al., Proc Natl Acad Sci U S A 2010
:
BDNF induces axonal sprouting through
Dock dependent
Rac activation, and adult transgenic mice overexpressing Dock3 exhibit enhanced optic nerve regeneration after injury without affecting WAVE expression levels
Kulkarni et al., J Biol Chem 2011
:
Multiple factors confer specific Cdc42 and
Rac protein
activation by
dedicator of cytokinesis ( DOCK ) nucleotide exchange factors
Kiyokawa et al., Genes Dev 1998
:
Activation of
Rac1 by a Crk SH3 binding protein,
DOCK180