Gene interactions and pathways from curated databases and text-mining

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S1PR1 — SPP1

Text-mined interactions from Literome

Hla et al., Prostaglandins Other Lipid Mediat 2001 : In vascular endothelial cells, SPP acts on EDG-1 and EDG-3 subtypes of receptors to induce cell survival and morphogenesis
Lee et al., Science 1998 : SPP activated the heterotrimeric guanine nucleotide binding protein ( G protein ) -coupled orphan receptor EDG-1 , originally cloned as Endothelial Differentiation Gene-1