Gene interactions and pathways from curated databases and text-mining

◀ Back to TNF

PDGFA — TNF

Text-mined interactions from Literome

Nishida et al., Kidney Int Suppl 1999 : Exposure to VLDL, IDL, LDL, or a high concentration of HDL enhanced the secretion of IL-6, PDGF-AB , and TGF-beta by mesangial cells, whereas TNF-alpha secretion was stimulated by oxidized LDL
Zhang et al., J Dermatol 1995 (Carcinoma, Squamous Cell) : Prostaglandin E1 slightly inhibited PDGF-AB production, transforming growth factor beta 1 promoted PDGF-AB production and interferon-gamma, interleukin-1 alpha, and tumor necrosis factor-alpha failed to exert any influence at all
Battegay et al., J Immunol 1995 : TNF-alpha induces PDGF A chain gene expression with a maximum at 4 h. DNA synthesis is abrogated in response to TNF-alpha by a goat anti-PDGF IgG but not by nonimmune goat IgG, suggesting induction of an autocrine PDGF-AA loop by TNF-alpha
Kose et al., J Cell Physiol 1996 : We now report that TNF-alpha significantly reduces PDGF-AA binding by decreasing the number of PDGF-alpha receptor subunits on the surface of normal human osteoblastic cells