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PDGFA — TNF
Text-mined interactions from Literome
Nishida et al., Kidney Int Suppl 1999
:
Exposure to VLDL, IDL, LDL, or a high concentration of HDL
enhanced the secretion of IL-6,
PDGF-AB , and TGF-beta by mesangial cells, whereas
TNF-alpha secretion was stimulated by oxidized LDL
Zhang et al., J Dermatol 1995
(Carcinoma, Squamous Cell) :
Prostaglandin E1 slightly inhibited PDGF-AB production, transforming growth factor beta 1
promoted PDGF-AB production and interferon-gamma, interleukin-1 alpha, and
tumor necrosis factor-alpha failed to exert any influence at all
Battegay et al., J Immunol 1995
:
TNF-alpha induces
PDGF A chain gene expression with a maximum at 4 h. DNA synthesis is abrogated in response to TNF-alpha by a goat anti-PDGF IgG but not by nonimmune goat IgG, suggesting induction of an autocrine PDGF-AA loop by TNF-alpha
Kose et al., J Cell Physiol 1996
:
We now report that
TNF-alpha significantly
reduces PDGF-AA binding by decreasing the number of PDGF-alpha receptor subunits on the surface of normal human osteoblastic cells