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CASP1 — ESR2

Text-mined interactions from Literome

Totta et al., J Nutr 2005 (Neoplasms) : The data show that D and some but not all of its metabolites 1 ) induce promoter activity, 2 ) reduce proliferation, 3 ) promote p38/mitogen activated protein kinase ( MAPK ) phosphorylation, and 4 ) activate a proapoptotic cascade involving the cleavage of caspase-3 and its substrate poly ( ADP-ribose ) polymerase ( PARP ) in human cancer cells in an ERbeta dependent manner
Hartman et al., Cancer Res 2009 (Colonic Neoplasms) : The second cdk2-inhibitor, p27 ( Kip1 ), was induced by ERbeta, but this regulation occurred at the posttranscriptional level, probably through ERbeta mediated repression of the F-box protein p45 ( Skp2 )