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EPHB2 — KCNH8
Text-mined interactions from Literome
Kelemen et al., J Biol Chem 2002
(MAP Kinase Signaling System) :
In addition, cell-permeable peptides inhibited
ERK mediated activation of the transcriptional activity of
ELK1
Koncz et al., Immunol Lett 2002
:
We compared the BCR
induced intracellular [ Ca2+ ] transient, protein tyrosine phosphorylation and
ERK phosphorylation, furthermore, the activation of
Elk-1 and CREB transcription factors
Adiseshaiah et al., J Immunol 2006
(MAP Kinase Signaling System) :
ERK inhibition not only
blocked phosphorylation of
Elk1 , CREB, and ATF1, which constitutively bind to the FRA-1 promoter, but also suppressed the recruitment of c-Jun to the promoter ... Our findings collectively indicate that
ERK signaling
plays key roles in both
Elk1 , CREB, and ATF-1 activation and the subsequent recruitment of c-Jun to the FRA-1 promoter in response to TNF-alpha in pulmonary epithelial cells
Ronda et al., J Steroid Biochem Mol Biol 2007
:
1alpha,25 ( OH ) ( 2 ) D ( 3 ) and 17beta-estradiol also induced the phosphorylation of CREB and
Elk-1 transcription factors in an
ERK1/2 dependent manner
Cohen-Armon et al., Mol Cell 2007
(MAP Kinase Signaling System) :
In cortical neurons treated with nerve growth factors and in stimulated cardiomyocytes, PARP-1 activation enhanced
ERK induced
Elk1-phosphorylation , core histone acetylation, and transcription of the Elk1-target gene c-fos
Lerner-Marmarosh et al., Proc Natl Acad Sci U S A 2008
(MAP Kinase Signaling System) :
hBVR is a nuclear transporter of ERK ; experiments with hBVR nuclear export signal (NES) and nuclear localization signal ( NLS ) mutants demonstrated its critical
role in the nuclear localization of IGF stimulated
ERK for
Elk1 activation
Ligeza et al., FEBS J 2008
:
Silencing of CREB or
Elk-1 significantly
increased ERK activation observed after 5 min of morphine stimulation
Hong et al., Mol Cell Biochem 2010
:
Further,
ERK inhibitor
inhibited significantly OPN expression,
Elk1 phosphorylation, and activator protein-1 (AP-1)-DNA binding activation, but not FAK phosphorylation, in the force applied cells
Gibbs et al., J Biol Chem 2012
:
Formation of ternary complex of human biliverdin reductase-protein kinase Cd-ERK2 protein is essential for
ERK2 mediated activation of
Elk1 protein, nuclear factor-?B, and inducible nitric-oxidase synthase (iNOS)