Gene interactions and pathways from curated databases and text-mining

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DES — NR5A1

Text-mined interactions from Literome

Emmen et al., Endocrinology 2000 (Cryptorchidism) : Furthermore, the effect of DES on steroidogenic factor 1 (SF-1) mRNA expression level was determined, since it has been shown that SF-1 plays an essential role in transcriptional activation of the Insl3 gene promoter
Zhang et al., Chin Med J (Engl) 2009 (Cryptorchidism...) : The effect of DES on steroidogenic factor-1 (SF-1) , that has been reported to control transcription of insulin-like factor 3 (INSL3), was also investigated
Visser et al., Endocrinology 1998 : In DES exposed male fetuses, SF-1 showed a similar increase in mRNA expression as AMH, in agreement with the observations that the AMH gene promoter requires an intact SF-1 DNA binding site for time- and cell-specific expression, although an effect of DES on SF-1 expression in other tissues, such as the adrenal and pituitary gland, can not be excluded