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DES — NR5A1
Text-mined interactions from Literome
Emmen et al., Endocrinology 2000
(Cryptorchidism) :
Furthermore, the
effect of
DES on
steroidogenic factor 1 (SF-1) mRNA expression level was determined, since it has been shown that SF-1 plays an essential role in transcriptional activation of the Insl3 gene promoter
Zhang et al., Chin Med J (Engl) 2009
(Cryptorchidism...) :
The
effect of
DES on
steroidogenic factor-1 (SF-1) , that has been reported to control transcription of insulin-like factor 3 (INSL3), was also investigated
Visser et al., Endocrinology 1998
:
In DES exposed male fetuses, SF-1 showed a similar increase in mRNA expression as AMH, in agreement with the observations that the AMH gene promoter requires an intact SF-1 DNA binding site for time- and cell-specific expression, although an
effect of
DES on
SF-1 expression in other tissues, such as the adrenal and pituitary gland, can not be excluded