UCSC Genome Browser Gene Interaction Graph

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Gene interactions and pathways from curated databases and text-mining

◀ Back to IGF1R

CTNND1 — IGF1R

Pathways - manually collected, often from reviews:

NCI Pathway Database Posttranslational regulation of adherens junction stability and dissassembly: E-cadherin/Ca2+/beta catenin/alpha catenin/p120 catenin complex (CDH1-CTNNB1-CTNNA1-CTNND1) → IGF-1R heterotetramer/IGF2 complex (IGF2-IGF1R) (translocation, collaborate)
Morali et al., Oncogene 2001
Evidence: physical interaction
NCI Pathway Database Stabilization and expansion of the E-cadherin adherens junction: E-cadherin/Ca2+/beta catenin/alpha catenin/p120 catenin complex (CDH1-CTNNB1-CTNNA1-CTNND1) → IGF-1R heterotetramer complex (IGF1R) (modification, inhibits)
Qian et al., EMBO J 2004
Evidence: assay, physical interaction