We have a suspicion that you are an automated web bot software, not a real user. To keep our site fast for other users, we have slowed down this page. The slowdown will gradually disappear. If you think this is a mistake, please contact us at genome-www@soe.ucsc.edu. Also note that all data for hgGeneGraph can be obtained through our public MySQL server and all our software source code is available and can be installed locally onto your own computer. If you are unsure how to use these resources, do not hesitate to contact us.
UCSC Genome Browser Gene Interaction Graph
Gene interactions and pathways from curated databases and text-mining

◀ Back to MAPK11

ADORA3 — MAPK11

Text-mined interactions from Literome

Robinson et al., Eur J Pharmacol 2001 : Furthermore, adenosine A(1) receptor mediated increases in p42/p44 MAPK were sensitive to the MAPK kinase 1 inhibitor PD 98059 ( 2'-amino-3'-methoxyflavone ), whereas p38 MAPK responses were blocked by the p38 MAPK inhibitor SB 203580 ( 4- ( 4-fluorophenyl ) -2- ( 4-methylsulfinylphenyl ) -5- ( 4-pyridyl ) 1H-imidazole ) ... Finally, adenosine A(1) receptor stimulation in DDT ( 1 ) MF-2 cells also activated p38 MAPK but not JNK via a pertussis toxin-sensitive pathway
Graham et al., Eur J Pharmacol 2001 : The high affinity adenosine A3 receptor agonist IB-MECA ( 1-deoxy-1- [ 6- [ [ ( 3-iodophenyl ) methyl ] amino ] -9H-purin-9-yl ] -N-methyl-beta-D-ribofuranuronamide ) stimulated time ( peak activation occurring after 5 min ) and concentration dependent ( pEC50=9.0+/-0.2 ) increases in p42/p44 MAPK in CHO-A3 cells ... In contrast, inhibition of protein kinase C had no significant effect on adenosine A3 receptor induced p42/p44 MAPK activation ... In conclusion, we have shown that the human adenosine A3 receptor stimulates p42/p44 MAPK and c-fos mediated luciferase gene expression in transfected CHO cells