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DYT22 — EEF1A2
Text-mined interactions from Literome
Krack et al., Brain 1999
(Chorea...) :
After acute levodopa challenge, high-frequency stimulation of the
STN reduced diphasic mobile
dystonia by 50 % and peak-dose choreic dyskinaesias by 30 % ... Acute high-frequency stimulation of the
STN mimics an acute levodopa challenge, concerning both parkinsonism and dyskinaesias, and
suppresses off-period
dystonia
Detante et al., Adv Neurol 2004
(Dystonia...) :
Assuming that the mechanism of action of STN-HFS is similar regardless of the cause of dystonia, our findings suggest that the
STN is not similarly
involved in off-period
dystonia of IPD and others dystonias
Lyons et al., J Neurosurg 2006
(Disorders of Excessive Somnolence...) :
Bilateral
STN DBS increased total sleep time and
reduced patient reported sleep problems and early morning
dystonia for up to 24 months posttreatment