Gene interactions and pathways from curated databases and text-mining

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Text-mined interactions from Literome

Hu et al., Biomaterials 2010 (Body Weight) : Moreover, TiO ( 2 ) NPs significantly inhibited the activities of Na ( + ) /K ( + ) -ATPase, Ca ( 2+ ) -ATPase, Ca ( 2+ ) /Mg ( 2+ ) -ATPase, acetylcholine esterase, and nitric oxide synthase ; the function of the central cholinergic system was also noticeably disturbed and the contents of some monoamines neurotransmitters such as norepinephrine, dopamine and its metabolite 3, 4-dihydroxyphenylacetic acid, 5-hydroxytryptamine and its metabolite 5-hydroxyindoleacetic acid were significantly decreased, while the contents of acetylcholine, glutamate, and nitric oxide were significantly increased
Li et al., Biol Trace Elem Res 2012 (Disease Resistance) : In addition, the TiO ( 2 ) NPs significantly promoted the expression of resistance related genes, including those encoding superoxide dismutase, catalase, glutathione peroxidase, acetylcholine esterase, carboxylesterase, heat shock protein 21, glutathione S transferase o1, P53, and transferring and of genes encoding cytochrome p302 and nitric oxide synthase
Liu et al., Biomaterials 2013 (Brain Ischemia) : Furthermore, CBSA-PEG-TIIA-NPs significantly decreased the mRNA expressions of iNOS and p38MAPK, upregulated PPAR? expression, and inhibited the protein levels of iNOS , GFAP and p38MAPK phosphorylation