Gene interactions and pathways from curated databases and text-mining

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CALML3 — IL10

Text-mined interactions from Literome

Song et al., J Trauma 2002 (Sepsis) : Splenic T-cell p38 MAPK activation and interleukin (IL)-10 release was increased by CLP , whereas Th1 cytokine ( IL-2, interferon-gamma ) release was depressed
Ohmura et al., Shock 2006 (Colonic Neoplasms...) : ( b ) CLP significantly increased the IL-10 level in serum, the IL-10 gene expression by spleen cells, the number of IL-10 producing CD4 positive T cells, and the productivity of IL-10 by spleen of tumor bearing mice compared with that of non-tumor bearing mice
Overhaus et al., Shock 2009 (Disease Models, Animal...) : Cecal ligation and puncture and simultaneous HS + CLP caused significant inflammatory messenger RNA induction of IL-6, iNOS, IL-10 , and heme oxygenase 1 compared with control and HS, and these responses were significantly suppressed in HS + delayed CLP colonic muscularis extracts
Hu et al., J Immunol 2009 (Inflammation...) : In this respect, when mice were pretreated in vivo with anti-CD1d blocking Ab, we observed not only that this inhibited the systemic rise of IL-6 and IL-10 levels in septic mice and improved overall septic survival, but that the CLP induced changes in liver macrophage IL-6 and IL-10 expressions were inversely effected by this treatment
Sha et al., Shock 2011 (Sepsis) : Treatment with TAK-242 ( 10 mg/kg i.v. ) in combination with imipenem ( 1 mg/kg s.c. ) 1 h after CLP significantly increased the survival rates of mice from 17 % to 50 % ( P = 0.01 ) and suppressed CLP induced increases in serum levels of IL-1[beta ], IL-6, IL-10 , and macrophage inflammatory protein 2 by 64 %, 73 %, 79 %, and 81 %, respectively ( P = 0.025 )
Li et al., Med Sci Monit 2011 (Respiratory Distress Syndrome, Adult...) : In comparison to group CLP/saline, plasma IL-10 level markedly increased in group CLP/PHC