Gene interactions and pathways from curated databases and text-mining

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CXCR2 — PLD2

Text-mined interactions from Literome

Lehman et al., Blood 2006 : Thus, PLD1 is differentially activated by CXCR-1, whereas CXCR-2 ( and possibly CXCR-1 ) mediates PLD2 activation
Bacon et al., J Immunol 1995 : Together, these results demonstrate that the IL-8RB receptor is sufficient to mediate phospholipase C (PLC) and PLD activation in T lymphocytes, but not in neutrophils, and indicate an important difference in receptor usage and signal transduction pathways between IL-8 stimulated lymphocytes and neutrophils