Nawa et al., Cell Signal 2008
(Amyotrophic Lateral Sclerosis) :
In agreement with BTBD10 mediated upregulation of the Akt phosphorylation levels, enforced expression of BTBD10 led to the suppression of mutant SOD1 induced neuronal death
Nawa et al., Cell Death Differ 2012
:
BTBD10 , an Akt interactor, activates Akt by decreasing the protein phosphatase 2A-mediated dephosphorylation and inactivation of Akt