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CCL2 — FAS

Text-mined interactions from Literome

Shimada et al., J Gastroenterol Hepatol 2001 (Adenocarcinoma...) : The pretreatment with interferon (IFN)-gamma markedly enhanced the effects of Fas Ag stimulation ; IFN-gamma pretreatment and Fas Ag stimulation synergistically induced not only apoptosis but also IL-8 and MCP-1 secretion
Shin et al., Yonsei Med J 2002 (Carcinoma, Hepatocellular...) : Conclusively, TGF-beta2, IL-8 and MCP-1 were overexpressed in HBV associated hepatoma cells, and the expressions of chemokines were not increased by Fas ligation in human hepatoma cells
Yamaoka-Tojo et al., Coron Artery Dis 2003 : Fas neutralizing agent ( Fas-Fc ) suppressed the Fas mediated secretions of IL-8 and MCP-1 ( P < 0.01 ) both as well as the Fas mediated apoptosis ... On the other hand, whereas Z-IETD-FMK suppressed apoptosis, the inhibitor enhanced the Fas mediated secretions of both IL-8 and MCP-1 beyond the value of the Fas stimulation alone ( P < 0.01 ), suggesting an enhanced signalling for the chemokine expression
Schaub et al., Circ Res 2003 : Fas and Fas associated death domain protein regulate monocyte chemoattractant protein-1 expression by human smooth muscle cells through caspase- and calpain dependent release of interleukin-1alpha ... In this study, we demonstrate that Fas/FADD induced MCP-1 upregulation is driven by an autocrine/paracrine signaling loop in which interleukin (IL)-1alpha synthesis and release are activated through caspase- and calpain dependent processes ... These data suggest that calpains play a dominant role in Fas/FADD induced IL-1alpha release and MCP-1 upregulation and that caspase activation may function to amplify the effects of calpain activation
Fujiwara et al., J Dermatol 2007 (Inflammation...) : Fas mediated upregulation of vascular endothelial growth factor and monocyte chemoattractant protein-1 expression in cultured dermal fibroblasts : role in the inflammatory response
Li et al., Sheng Li Xue Bao 2010 (Atherosclerosis) : As shown in our preliminary study, MCP-1 induced apoptosis of hUVECs in a dose dependent manner at both 24 h and 48 h. FACS and Western blot analysis results in the present study indicated that MCP-1 promoted the expression of proapoptotic proteins Bax and Fas and inhibited the expression of antiapoptotic protein Bcl-2
Fluhr et al., Mol Hum Reprod 2011 : In contrast, IL-6, MCP-1 and RANTES were not regulated by Fas
Akiyama et al., Cell stem cell 2012 (Colitis...) : Mechanistic analysis revealed that FAS regulated monocyte chemotactic protein 1 (MCP-1) secretion by BMMSCs recruited T cells for FASL mediated apoptosis
Cullen et al., Mol Cell 2013 : Fas induced production of MCP-1 and IL-8 promoted chemotaxis of phagocytes toward apoptotic cells, suggesting that these factors serve as `` find-me '' signals in this context